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Orthopedic Surgery (Pediatrics)

Management and Optimization of Hemostasis

Antifibrinolytic Agents

A systematic review of the use of antifibrinolytic agents in pediatric surgery and implications for craniofacial use. (opens new window)

Basta MN, Stricker PA, Taylor JA.

Source‎: Pediatr Surg Int 2012;28(11):1059-69.

Indexed‎: PubMed 22940882

DOI‎: 10.1007/s00383-012-3167-6

https://www.ncbi.nlm.nih.gov/pubmed/22940882 (opens new window)

Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study. (opens new window)

Elwatidy S, Jamjoom Z, Elgamal E, Zakaria A, Turkistani A, El-Dawlatly A.

Source‎: Spine (Phila Pa 1976) 2008;33(24):2577-80.

Indexed‎: PubMed 19011538

DOI‎: 10.1097/BRS.0b013e318188b9c5

https://www.ncbi.nlm.nih.gov/pubmed/19011538 (opens new window)

Tranexamic acid is efficacious at decreasing the rate of blood loss in adolescent scoliosis surgery: a randomized placebo-controlled trial. (opens new window)

Goobie SM, Zurakowski D, Glotzbecker MP, McCann ME, Hedequist D, Brustowicz RM, Sethna NF, Karlin LI, Emans JB, Hresko MT

Source‎: J Bone Joint Surg Am 2018;100(23):2024-32.

Indexed‎: PubMed 30516625

DOI‎: 10.2106/JBJS.18.00314

https://www.ncbi.nlm.nih.gov/pubmed/30516625 (opens new window)

Antifibrinolytic agents reduce blood loss during pediatric vertebral column resection procedures. (opens new window)

Newton PO, Bastrom TP, Emans JB, Shah SA, Shufflebarger HL, Sponseller PD, Sucato DJ, Lenke LG.

Source‎: Spine (Phila Pa 1976) 2012;37(23):E1459-63.

Indexed‎: PubMed 22872217

DOI‎: 10.1097/BRS.0b013e31826c9fe4

https://www.ncbi.nlm.nih.gov/pubmed/22872217 (opens new window)

The effect of aprotinin, tranexamic acid, and aminocaproic acid on blood loss and use of blood products in major pediatric surgery: a meta-analysis. (opens new window)

Schouten ES, van de Pol AC, Schouten AN, Turner NM, Jansen NJ, Bollen CW.

Source‎: Pediatr Crit Care Med 2009;10(2):182-90.

Indexed‎: PubMed 19188875

DOI‎: 10.1097/PCC.0b013e3181956d61

https://www.ncbi.nlm.nih.gov/pubmed/19188875 (opens new window)

The role of Amicar in same-day anterior and posterior spinal fusion for idiopathic scoliosis. (opens new window)

Thompson GH, Florentino-Pineda I, Poe-Kochert C, Armstrong DG, Son-Hing JP.

Source‎: Spine (Phila Pa 1976) 2008;33(20):2237-42.

Indexed‎: PubMed 18794767

DOI‎: 10.1097/BRS.0b013e31817bd889

https://www.ncbi.nlm.nih.gov/pubmed/18794767 (opens new window)

Does the intraoperative tranexamic acid decrease operative blood loss during posterior spinal fusion for treatment of adolescent idiopathic scoliosis? (opens new window)

Yagi M, Hasegawa J, Nagoshi N, Iizuka S, Kaneko S, Fukuda K, Takemitsu M, Shioda M, Machida M.

Source‎: Spine (Phila Pa 1976) 2012;37(21):E1336-42.

Indexed‎: PubMed 22772572

DOI‎: 10.1097/BRS.0b013e318266b6e5

https://www.ncbi.nlm.nih.gov/pubmed/22772572 (opens new window)

Coagulation Factor Concentrates

Higher fibrinogen concentrations for reduction of transfusion requirements during major paediatric surgery: a prospective randomised controlled trial. (opens new window)

Haas T, Spielmann N, Restin T, Seifert B, Henze G, Obwegeser J, Min K, Jeszenszky D, Weiss M, Schmugge M.

Source‎: Br J Anaesth 2015;115(2):234-43.

Indexed‎: PubMed 25982134

DOI‎: 10.1093/bja/aev136

https://www.ncbi.nlm.nih.gov/pubmed/25982134 (opens new window)

Viscoelastic Tests to Identify Surgical or Coagulopathic Bleeding

Higher fibrinogen concentrations for reduction of transfusion requirements during major paediatric surgery: a prospective randomised controlled trial. (opens new window)

Haas T, Spielmann N, Restin T, Seifert B, Henze G, Obwegeser J, Min K, Jeszenszky D, Weiss M, Schmugge M.

Source‎: Br J Anaesth 2015;115(2):234-43.

Indexed‎: PubMed 25982134

DOI‎: 10.1093/bja/aev136

https://www.ncbi.nlm.nih.gov/pubmed/25982134 (opens new window)